![]() Telekinesis: Automatically blocks any incoming shots, but the push is not strong enough to prevent contact damage.Tainted Forgotten: Triggers his active item whenever the body touches something that would damage The Soul, regardless of damage taken.Stitches: Isaac will teleport before damage is taken, making him much harder to hit.Spin to Win: Has a chance to spawn additional wheels upon taking damage that last only for the current room.Razor Blade: Isaac gains a damage boost every time he's hit, acting similarly to Red Patch, at the cost of every hit making Isaac take full-heart damage.My Little Unicorn: Gives invulnerability and +0.28 speed for six seconds, removing the ability to shoot tears and replacing it with the ability to deal contact damage to enemies.Kamikaze!: Causes a highly-damaging explosion to occur every time Isaac is hit, similarly to Swallowed M80.IV Bag: Upon getting hit, activates the IV Bag instead, causing self-damage and producing money.How to Jump: Makes Isaac immune to contact and tear damage while moving.The Lost can die this way should he carry self damaging items at the time of the hit.Holy Mantle: Does not stop the trinket from activating, making Isaac still take damage from items such as IV Bag, while bypassing Holy Mantle's shield.Glowing Hour Glass: If consumed with Void, every time Isaac is hit, if it's charged, he is sent back to the previous room without taking damage.If combined with 9 Volt or AAA Battery, works every room, just like Holy Mantle. Dull Razor: Activates the item and gives Isaac invincibility frames before being hit, making it work similarly to Holy Mantle every two rooms.Note that this does not work while playing as Tainted Judas. Dark Arts: Unlike many other items on this list, Dark Arts can be used to negate damage more than once per room, making it an excellent defensive item to use with Panic Button.Butter Bean / Wait What?: Isaac farts before being hit, knocking back enemies and projectiles.Bursting Sack: Even though the neutral spiders spawned by the item can't possibly hurt Isaac, the trinket still activates when contact is made with them.Book of Shadows: Activates the item, giving Isaac the shield effect for 10 seconds.Blood Rights: Triggers the effect on hit, at the cost of every hit making Isaac take full-heart damage.Clear Rune with Rune of Algiz / Blank Rune / Rune Shard / Soul of Judas: Activate their respective effects without consuming it.Blank Card with VII - The Chariot / VII - The Chariot?: Activate their respective effects without consuming it.For self-damaging items that deals only half a heart damage (such as Kamikaze!), before chapter 4, it will also reduce enemy damage to half a heart, similarly to The Wafer.Any self-damaging item: Self-damage occurs before enemy damage, making it almost impossible to lose Devil/Angel Room chances.This effect still occurs even whilst he is chained by Anima Sola, when he deals no contact damage.Will activate when touching Dark Esau while playing as Tainted Jacob, despite Dark Esau not technically dealing damage.Does not activate items in a consumable slot (such as Tainted Bethany's Lemegeton or dice items granted by Dice Bag).This is NOT an effect by Mom's Box or the Golden Trinket variant. Super-charged items will use both of their charges.Taking damage from explosions, enemy creep, spikes and spike rocks, Spiked Chest and Mimic Chest, the stomp attacks from Mom and Satan, Whipper and their variants, brimstone lasers (including angel lasers), electric lasers, self-damage items, Devil Beggar, Hell Game, Blood Donation Machine, and Confessional will not trigger the effect.Because the automatic item activation takes place just before taking would-be damage, this trinket becomes very powerful when holding damage-negating active items. ![]() This still uses the item's charges so if the item is not charged, the trinket will do nothing.Activates Isaac's active item just before damage would be taken.
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